Query Information
ORIGIN plant
BEGIN
>MYSEQ
NKIRSYGSTR WTDHDVVRLM LRSFTVLDPH LVNNIRENPR YTKMTPEEVL
GKFVSGRMMI KEARYVDDAL NGPINEPQPL ARKAMRSKEA LPSKVAQVEA
AVLNNEEMAL IIKRFKTALK GRKGQPSKTK TKEKRSCFKC GKIGHFIANC
PENESDQEKG NKREKKKHYK KAKGEAHIGK EWDLDCSSSD SDNEGLAATA
FNKSSLFPNE RHTCLMAREK KVS
Result Information
PSORT --- Prediction of Protein Localization Sites
version 6.4(WWW)
MYSEQ 223 Residues
*** Warning: The 1st amino acid is not methionine
Species classification: 5
*** Reasoning Step: 1
Preliminary Calculation of ALOM (threshold: 0.5)
count: 0
McG: Examining signal sequence (McGeoch)
Length of UR: 2
Peak Value of UR: 1.31
Net Charge of CR: 3
Discriminant Score: -6.41
GvH: Examining signal sequence (von Heijne)
Signal Score (-3.5): -4.38
Possible cleavage site: 29
>>> Seems to have no N-terminal signal seq.
Amino Acid Composition of Predicted Mature Form:
calculated from 1
ALOM new cnt: 0 ** thrshld changed to -2
Cleavable signal was detected in ALOM?: 0B
ALOM: finding transmembrane regions (Klein et al.)
count: 0 value: 4.77 threshold: -2.0
PERIPHERAL Likelihood = 4.77
modified ALOM score: -1.85
Gavel: Examining the boundary of mitochondrial targeting seq.
motif at: 12
TRWTDH
Discrimination of mitochondrial target seq.:
notclr ( 0.12)
Rule: mitochondrial protein
Rule: mitochondrial protein
Rule: mitochondrial protein
Rule: mitochondrial protein
Hydrophobic moment analysis for chloroplast proteins
Hmax: 7.41 at (69)
Disc.Score from Amino Acid Composition (chloroplast)
score from the 3-11 region: 0.11
score from the 1-31 region: 4.08
Chloroplast protein? Status: negative (-8.45)
*** Reasoning Step: 2
KDEL Count: 0
Checking apolar signal for intramitochondrial sorting
(Gavel position 12) from: 19 to: 21 Score: 2.5
Mitochondrial matrix? Score: 0.36
Checking apolar signal for intrachloroplastic sorting
Howe: Checking the consensus for intrachloropl.sorting
SKL motif (signal for peroxisomal protein):
pos: -1(223), count: 0
Amino Acid Composition Tendency for Peroxisome: -4.90
Peroxisomal proteins? Status: negative
Amino acid composition tendency for vacuolar proteins
Score: 1.75 Status: notclr
Checking the amount of Basic Residues (nucleus)
Highly rich in K&R: 20.2% ( 0.31)
Checking the 4 residue pattern for Nuclear Targeting
Found: pos: 164 (3) KKKH
Checking the 7 residue pattern for Nuclear Targeting
Checking the Robbins & Dingwall consensus (nucleus)
Checking the RNA binding motif (nucleus or cytoplasm)
nuc modified. Score: 0.80
Nuclear Signal Status: notclr ( 0.60)
Checking CaaX motif..
Checking N-myristoylation..
Checking CaaX motif..
----- Final Results -----
nucleus --- Certainty= 0.724(Affirmative) < succ>
mitochondrial matrix space --- Certainty= 0.432(Affirmative) < succ>
mitochondrial inner membrane --- Certainty= 0.112(Affirmative) < succ>
mitochondrial intermembrane space --- Certainty= 0.112(Affirmative) < succ>
----- The End -----