Query Information
ORIGIN plant
BEGIN
>MYSEQ
KRRKKNAERH IAKRIAYFNV VNVVQELCGQ PSSGHLDGQE VSVHPNLPSI
KKMTSGWICK GVYEPVKSKG RTGLILENPN LTEKFFFSSF LSGLKEEVKY
MVTAQHPTLI VTRLMNMLCT MSHLSQPVRN LEWYLGAEFR KRERGSLQTT
AFFLLMRFAL ERQKWKETER RLVKPISPKK RKMTLTSTVG KSSFPEWIQS
NAEVEQYQGS VLGQTESWIR GSFLA
Result Information
PSORT --- Prediction of Protein Localization Sites
version 6.4(WWW)
MYSEQ 225 Residues
*** Warning: The 1st amino acid is not methionine
Species classification: 5
*** Reasoning Step: 1
Preliminary Calculation of ALOM (threshold: 0.5)
count: 0
McG: Examining signal sequence (McGeoch)
Length of UR: 2
Peak Value of UR: 1.41
Net Charge of CR: 6
Discriminant Score: -3.71
GvH: Examining signal sequence (von Heijne)
Signal Score (-3.5): -4.51
Possible cleavage site: 29
>>> Seems to have no N-terminal signal seq.
Amino Acid Composition of Predicted Mature Form:
calculated from 1
ALOM new cnt: 0 ** thrshld changed to -2
Cleavable signal was detected in ALOM?: 0B
ALOM: finding transmembrane regions (Klein et al.)
count: 0 value: 4.72 threshold: -2.0
PERIPHERAL Likelihood = 4.72
modified ALOM score: -1.84
Gavel: Examining the boundary of mitochondrial targeting seq.
motif at: 16
KRIAYF
Discrimination of mitochondrial target seq.:
notclr ( 0.80)
Rule: mitochondrial protein
Rule: mitochondrial protein
Rule: mitochondrial protein
Rule: mitochondrial protein
Hydrophobic moment analysis for chloroplast proteins
Hmax: 10.87 at (40)
Disc.Score from Amino Acid Composition (chloroplast)
score from the 3-11 region: -1.85
score from the 1-31 region: 4.87
Chloroplast protein? Status: negative (-8.65)
*** Reasoning Step: 2
KDEL Count: 0
Checking apolar signal for intramitochondrial sorting
(Gavel position 16) from: 15 to: 18 Score: 2.5
Mitochondrial matrix? Score: 0.36
Checking apolar signal for intrachloroplastic sorting
Howe: Checking the consensus for intrachloropl.sorting
SKL motif (signal for peroxisomal protein):
pos: 122(225), count: 1 SHL
SKL score (peroxisome): 0.3
Amino Acid Composition Tendency for Peroxisome: 2.37
Peroxisomal proteins? Status: positive
AAC score (peroxisome): 0.383
Amino acid composition tendency for vacuolar proteins
Score: -6.49 Status: negative
Checking the amount of Basic Residues (nucleus)
Checking the 4 residue pattern for Nuclear Targeting
Found: pos: 1 (5) RRKK
Found: pos: 177 (4) PKKR
Found: pos: 178 (5) KKRK
Checking the 7 residue pattern for Nuclear Targeting
Checking the Robbins & Dingwall consensus (nucleus)
Checking the RNA binding motif (nucleus or cytoplasm)
nuc modified. Score: 0.90
Nuclear Signal Status: positive ( 0.70)
Checking CaaX motif..
Checking N-myristoylation..
Checking CaaX motif..
----- Final Results -----
nucleus --- Certainty= 0.700(Affirmative) < succ>
microbody (peroxisome) --- Certainty= 0.568(Affirmative) < succ>
mitochondrial matrix space --- Certainty= 0.475(Affirmative) < succ>
mitochondrial inner membrane --- Certainty= 0.180(Affirmative) < succ>
----- The End -----