Query Information
ORIGIN plant
BEGIN
>MYSEQ
EHQRRPLHRH RHGRHRHRRQ RQLQPGHQVR VLRPEQHHRL PRHQAEDIRA
QCRWPHTTGT AESYALDQSG FKQELLNRFF AIFPREFDCY AVHDFGHQCI
VWICSKGAWE PCESCISRLW LELLKWPPSL GVGKPGKTGA IPDTCGRRWG
KDLCWRCWQR PRRRRSRWSF RRSPILALYV YRHPSCNTSS FPSFSSPSCR
RPCHCHLYMD IQSDRTYHKK KKKK
Result Information
PSORT --- Prediction of Protein Localization Sites
version 6.4(WWW)
MYSEQ 224 Residues
*** Warning: The 1st amino acid is not methionine
Species classification: 5
*** Reasoning Step: 1
Preliminary Calculation of ALOM (threshold: 0.5)
count: 0
McG: Examining signal sequence (McGeoch)
Length of UR: 0
Peak Value of UR: -0.96
Net Charge of CR: 6
Discriminant Score: -20.92
GvH: Examining signal sequence (von Heijne)
Signal Score (-3.5): -6.76
Possible cleavage site: 60
>>> Seems to have no N-terminal signal seq.
Amino Acid Composition of Predicted Mature Form:
calculated from 1
ALOM new cnt: 0 ** thrshld changed to -2
Cleavable signal was detected in ALOM?: 0B
ALOM: finding transmembrane regions (Klein et al.)
count: 0 value: 7.53 threshold: -2.0
PERIPHERAL Likelihood = 7.53
modified ALOM score: -2.41
Gavel: Examining the boundary of mitochondrial targeting seq.
motif at: 35
LRPEQH
Discrimination of mitochondrial target seq.:
negative (-2.53)
Hydrophobic moment analysis for chloroplast proteins
Hmax: 9.20 at (46)
Disc.Score from Amino Acid Composition (chloroplast)
score from the 3-11 region: -2.77
score from the 1-31 region: 2.37
Chloroplast protein? Status: negative (-12.55)
*** Reasoning Step: 2
KDEL Count: 0
Checking apolar signal for intramitochondrial sorting
Mitochondrial matrix? Score: 0.10
Checking apolar signal for intrachloroplastic sorting
Howe: Checking the consensus for intrachloropl.sorting
SKL motif (signal for peroxisomal protein):
pos: 117(224), count: 1 SRL
SKL score (peroxisome): 0.3
Amino Acid Composition Tendency for Peroxisome: 5.78
Peroxisomal proteins? Status: positive
AAC score (peroxisome): 0.640
Amino acid composition tendency for vacuolar proteins
Score: -11.43 Status: negative
Checking the amount of Basic Residues (nucleus)
Highly rich in K&R: 20.1% ( 0.30)
Checking the 4 residue pattern for Nuclear Targeting
Found: pos: 15 (3) RHRR
Found: pos: 159 (4) RPRR
Found: pos: 160 (4) PRRR
Found: pos: 161 (5) RRRR
Found: pos: 217 (3) HKKK
Found: pos: 218 (5) KKKK
Found: pos: 219 (5) KKKK
Found: pos: 220 (5) KKKK
Checking the 7 residue pattern for Nuclear Targeting
Checking the Robbins & Dingwall consensus (nucleus)
Found: pos: 3 (3) RR PLHRHRHGRH RHRRQ
Found: pos: 146 (3) RR WGKDLCWRCW QRPRR
Final Robbins Score (nucleus): 0.80
Checking the RNA binding motif (nucleus or cytoplasm)
nuc modified. Score: 0.90
Nuclear Signal Status: positive ( 0.90)
Checking CaaX motif..
Checking N-myristoylation..
Checking CaaX motif..
----- Final Results -----
nucleus --- Certainty= 0.986(Affirmative) < succ>
microbody (peroxisome) --- Certainty= 0.748(Affirmative) < succ>
mitochondrial matrix space --- Certainty= 0.100(Affirmative) < succ>
endoplasmic reticulum (membrane) --- Certainty= 0.000(Not Clear) < succ>
----- The End -----