Query Information
ORIGIN plant
BEGIN
>MYSEQ
CPPKGVRGRC RCPGRTRLLL TLEDHRKKPG TRACRERRTR GGRASTVSPG
HSMISTRGGY QAEKPGQVLY SPNVPIASAS RAPAPSSAGE AVTDLKSAFA
VRIDFCERLA PGIKKKTSAK FHFRSVNKPK KETFFARRRT MLRFNKEFSV
EPVNHASWLD AWGRGLVVPD SAAMQWKGRS LNRPPSFFFK KKKKK
Result Information
PSORT --- Prediction of Protein Localization Sites
version 6.4(WWW)
MYSEQ 195 Residues
*** Warning: The 1st amino acid is not methionine
Species classification: 5
*** Reasoning Step: 1
Preliminary Calculation of ALOM (threshold: 0.5)
count: 0
McG: Examining signal sequence (McGeoch)
Length of UR: 3
Peak Value of UR: 0.72
Net Charge of CR: 4
Discriminant Score: -9.55
GvH: Examining signal sequence (von Heijne)
Signal Score (-3.5): -7.25
Possible cleavage site: 58
>>> Seems to have no N-terminal signal seq.
Amino Acid Composition of Predicted Mature Form:
calculated from 1
ALOM new cnt: 0 ** thrshld changed to -2
Cleavable signal was detected in ALOM?: 0B
ALOM: finding transmembrane regions (Klein et al.)
count: 0 value: 8.06 threshold: -2.0
PERIPHERAL Likelihood = 8.06
modified ALOM score: -2.51
Gavel: Examining the boundary of mitochondrial targeting seq.
motif at: 19
TRLLLT
Discrimination of mitochondrial target seq.:
notclr ( 0.02)
Rule: mitochondrial protein
Rule: mitochondrial protein
Rule: mitochondrial protein
Rule: mitochondrial protein
Hydrophobic moment analysis for chloroplast proteins
Hmax: 7.84 at (69)
Disc.Score from Amino Acid Composition (chloroplast)
score from the 3-11 region: 1.08
score from the 1-31 region: 0.00
Chloroplast protein? Status: negative (-11.44)
*** Reasoning Step: 2
KDEL Count: 0
Checking apolar signal for intramitochondrial sorting
(Gavel position 19) from: 18 to: 22 Score: 3.5
Mitochondrial matrix? Score: 0.36
Checking apolar signal for intrachloroplastic sorting
Howe: Checking the consensus for intrachloropl.sorting
SKL motif (signal for peroxisomal protein):
pos: -1(195), count: 0
Amino Acid Composition Tendency for Peroxisome: 1.97
Peroxisomal proteins? Status: notclr
AAC score (peroxisome): 0.330
Amino acid composition tendency for vacuolar proteins
Score: -3.17 Status: negative
Checking the amount of Basic Residues (nucleus)
Highly rich in K&R: 22.6% ( 0.43)
Checking the 4 residue pattern for Nuclear Targeting
Found: pos: 24 (3) HRKK
Found: pos: 25 (4) RKKP
Found: pos: 127 (4) KPKK
Found: pos: 189 (5) KKKK
Found: pos: 190 (5) KKKK
Found: pos: 191 (5) KKKK
Checking the 7 residue pattern for Nuclear Targeting
Checking the Robbins & Dingwall consensus (nucleus)
Found: pos: 114 (3) KK TSAKFHFRSV NKPKK
Final Robbins Score (nucleus): 0.60
Checking the RNA binding motif (nucleus or cytoplasm)
nuc modified. Score: 0.90
Nuclear Signal Status: positive ( 0.90)
Checking CaaX motif..
Checking N-myristoylation..
Checking CaaX motif..
----- Final Results -----
nucleus --- Certainty= 0.977(Affirmative) < succ>
mitochondrial matrix space --- Certainty= 0.425(Affirmative) < succ>
microbody (peroxisome) --- Certainty= 0.330(Affirmative) < succ>
mitochondrial inner membrane --- Certainty= 0.102(Affirmative) < succ>
----- The End -----